Many of the problems in the mpox response were due to a deflated and exhausted public health workforce across the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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The 3 studies are the largest yet to measure how well the vaccine performed in the US amid the mpox outbreak of 2022.
Seven linked transmission chains were noted, including 3 patients who had linked partners who were female sex workers.
Sampling reveals considerably more mpox DNA than expected based on area cases and hospitalizations.
The severe case of mpox involved pulmonary illness.
Spring and summer gatherings and vaccination gaps are among the factors that could fuel another surge.
Countries have made steady progress with outbreaks, but the virus is still a threat in multiple world regions.
The organizations recommend 4 actions to help prevent and manage any future outbreaks.
The WHO declared a public health emergency of international concern in July 2022 following the global spread of the virus.
Local adverse event rates were highest following intradermal vaccine administration.
Africa has had a 7.4% case increase, with 111 new infections in the most recent 2 weeks.