A team of researchers from Harvard is developing synthetic antibiotics enhanced to overcome resistance mechanisms.
A population-based study in Shanghai finds COPD patients are nearly 8 times more likely to use antibiotics than the general population.
The CDC says other antibiotics should be considered for prevention among close contacts in areas where ciprofloxacin-resistant cases have been reported.
Gepotidacin showed non-inferiority in one phase 3 trial, and superiority in another, compared with first-line treatments for uncomplicated UTIs.
The portable test from Visby Medical will be able to detect gonorrhea and assess susceptibility to ciprofloxacin.
The low-cost lateral flow assay showed high sensitivity and specificity in 400 patients with symptoms of gonorrhea, and results were available in 30 minutes.
A brand of artificial tears manufactured in India was confirmed as the source of the multi-state outbreak.
A review of randomized controlled trials found that Asian and Black participants were underrepresented.
Treatment with the narrow-spectrum investigational antibiotic ridinilazole resulted in a 53% relative reduction of recurrent C difficile infection compared with vancomycin.
Researchers say antibiotic trials in children diagnosed as having community-acquired pneumonia likely include many children without radiographic pneumonia.
Four colonization cases have been reported in patients with links to the same long-term acute-care hospital.
The trial found that the anti-staphylococcal lycin exebacase plus standard-of-care antibiotics failed to improve clinical response compared with antibiotics alone.
An investigation of the clinic identified gaps in environmental cleaning practices, surgical device disinfection.
Among the exposures the study will evaluate is antibiotic use, which has been shown to disrupt the microbiome.
The findings highlight the need to boost infection prevention and control and antimicrobial stewardship efforts in Greek hospitals.
In the intention-to-treat population, the vaccine effectiveness of the typhoid vaccine was 78%.
The UK's Medicines and Healthcare products Registry says fluoroquinolones should be used only when no other appropriate antibiotics are available.
High use of Watch antibiotics was reported among patients in Ivory Coast, Burkina Faso, Democratic Republic of the Congo, and South Africa.
In a population-based study, patients recently exposed to antibiotics and proton pump inhibitors had an 18-fold increase in the risk of C diff infection.
The two groups will combine efforts to genetically track threats ranging from mosquito borne pathogens to pandemic flu.
The CRISPR-engineered bacteriophage therapy from Locus Biosciences targets urinary tract infections caused by drug-resistant E coli.
Lack of human resources, absence of leadership, and limited microbiology laboratory support are some of the issues cited.
Investigators say the strategy is readily applicable in low- and middle-income countries, where high rates of ventilator-associated pneumonia drive antibiotic use.
Reduced antibiotic consumption was related to de-escalation and discontinuation of empiric antibiotic therapy during the intervention period.
Investigators say switching to oral antibiotic therapy in patients with low risk of complications could simplify treatment and allow for earlier discharge.