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The University of Colorado (UC) School of Medicine announced yesterday that it's been awarded $5 million from the US Department of Defense (DoD) to collect and study data on antibiotic-resistant wounds linked to the war in Ukraine.
Wound infections caused by multidrug-resistant organisms have substantially increased in Ukraine since Russian forces invaded the country in 2022, complicating treatment for frontline providers. Yet no systematic data for wound infections exist in Ukraine. Through the project, called the Antimicrobial Resistance Research to Improve Outcomes of Traumatic Wounds study (ARROW) study, UC researchers will work with researchers in Ukraine to create infrastructure for collecting such data.
Wound infection a 'top concern' for US military
The project aims to enroll up to 1,000 patients and collect data on injury and wound characteristics, molecular testing, and clinical outcomes, with researchers in Ukraine collecting specimens at three frontline hospitals and two referral centers over the next 2 years. UC researchers say these data will help providers in Ukraine during the current conflict and enable clinical trials to test solutions that help prevent and treat wound infections in future conflicts.
"Wound infection is consistently identified as a top concern in Ukraine and the U.S. military, which is why we are moving forward on this project first," Adit Ginde, MD, MPH, a professor of emergency medicine at UC and principal investigator on the project, said in a UC press release. "The first step is actually describing the problem in a more systematic way and then quickly pivot[ing] to clinical trials."
Roman Fishchuk, MD, a researcher at Central City Clinical Hospital of Ivano-Frankivsk in western Ukraine, will lead the in-country data collection effort.
“I'm grateful to our colleagues at the University of Colorado for being brave, working with us, and being so proactive," Fishchuk said. "This partnership is inspiring and helps us do our job and think about research in new ways."