The loss may threaten the population's future by reducing the number of surviving pups and highlights the need for continued, intensive monitoring.
If confirmed, it will be the first human bird flu case in the US since February.
In the past 30 days officials have confirmed highly pathogenic avian flu in 31 commercial flocks and 31 backyard flocks across the United States.
In Michigan, 113,000 birds were affected on a turkey farm in Ottawa County, the state's third detection in commercial turkeys in less than a week.
Even without a booster, the vaccine triggered mucosal and systemic immunity, which other intranasal recombinant H5 flu vaccines have not achieved in clinical trials.
Elsewhere, 2 large poultry outbreaks were reported in Lagrange County, Indiana.
Grant County, Washington, recently had 7 avian flu detections in wild birds.
The findings highlight a critical gap in many national and global H5N1 surveillance systems.
In September cholera cases were down 27% from August.
Senegal's Rift Valley fever outbreak now has 302 confirmed cases.
