The study didn't specifically examine long-COVID outcomes, and the findings don't necessarily conflict with those of previous studies, the authors say.
The loss of activity is equivalent to 15% of the US population becoming completely immobile for 1 day.
Adult COVID-19 patients also infected with the flu are 4 times more likely to need mechanical ventilation and 2.4 times more likely to die.
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Some states in the Central and Midwest regions are reporting high or very high flu activity.
Wastewater COVID detections last week declined from the high to the moderate level.
A review and meta-analysis also finds no impact on length of stay in the emergency department, return visits, or hospitalization.
Flu is rising in central states, and COVID levels are highest but on the decline in southern states.
Flu activity increased in five regions: the Northeast, New England, the Middle Atlantic, the Midwest, and the Central states.
Though influenza A is still dominant, some countries are seeing influenza B rises.
Influenza B proportions are rising in regions where flu activity is trending upward.
The results suggest that the flu virus may have a more specific role in destabilizing and rupturing atherosclerotic plaques, the researchers say.
Influenza B activity is fueling rises in the Midwest and Central regions.
A phase 3 trial of the drug, focusing on the 600-mg dose, is under way.