A review and meta-analysis finds Salmonella Typhi and Paratyphi samples from human infections in Pakistan were highly resistant to first-line and other commonly used antibiotics.
Researchers say the introduction of typhoid conjugate vaccines in these countries could help protect communities, especially school-aged children.
In the intention-to-treat population, the vaccine effectiveness of the typhoid vaccine was 78%.
Montana's H1N2v case was reported in a patient who had attended an agricultural fair.
Genomic analysis of extensively drug-resistant typhoid isolates in Pakistan reveals numerous circulating XDR variants.
Typhoid fever has become increasingly resistant to antibiotics over the past 50 years.
A phase 3 clinical trial conducted in Malawi has found that a single dose of typhoid conjugate vaccine (TCV) is safe and more than 80% effective at protecting children against typhoid fever, an international team of researchers reported yesterday in the New England Journal of Medicine.
The agency confirms 9 cases not tied to international travel but says reporting for 2020 is not yet complete.
Researchers from the Centers for Disease Control and Prevention (CDC) have identified 33 cases of extensively drug-resistant (XDR) Salmonella enterica serotype Typhi in the United States linked to travel in Pakistan and Iraq, according to an update today in the CDC's Morbidity and Mortality Weekly Report (MMWR).
The efficacy of the conjugate vaccine was thus 82%, and it had a good safety profile.
