A systematic review and meta-analysis of randomized controlled trials examining antibiotic therapy for non-recurrent Clostridium difficile infections has found that fidaxomicin provides a sustained symptomatic cure most frequently, researchers reported yesterday in The Lancet Infectious Diseases.
Patients incorrectly labeled as allergic to penicillin are more likely to receive broad-spectrum antibiotics, a practice that promotes resistance.
The Behavioural Economics Team of the Australian Government, in partnership with Australia's Chief Medical Officer (CMO) and the Department of Health, released a new report showing that targeting high-prescribing physicians with a letter from the CMO helped lower the number of antibiotic prescriptions within 6 months.
Healthcare-related CDI fell from 5.9 to 4.3 per 10,000 patient-days, a 27% reduction.
Adding ultraviolet light to standard room cleaning modestly decreases hospital-wide superbugs.
A new study in the Journal of Drugs and Dermatology suggests that a diuretic drug may be as effective as antibiotics for treatment of women's acne.
Chinese scientists yesterday reported on the emergence of extensively drug-resistant (XDR) Escherichia coli carrying both New Delhi metallo-beta-lactamase (NDM) and MCR-1 genes in chickens at slaughter in China and detailed the features of two novel NDM-carrying plasmids.
A study today in the New England Journal of Medicine reports that childhood mortality in sub-Saharan African communities randomly assigned to mass distribution of azithromycin was lower than in those assigned a placebo. But the authors warn that resistance emerging from mass distribution of the antibiotic could curb or reverse any potential benefit.
A study yesterday in the American Journal of Infection Control has found that only 62% of reported cases of healthcare facility–onset Clostridium difficile (HO-CDI) at a New York hospital met clinical criteria.
A study group with the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) reports that 45% of specialists in infectious diseases and clinical microbiology sometimes worried and 29% often worried about malpractice implications when prescribing or advising on antibiotic prescriptions, and 85% reported defensive behaviors when prescribing, according to a study today in the Journal of Antimicrobial Ch