Mpox spread is occurring alongside a refugee crisis, internal violence, and a host of other disease outbreaks.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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Sensitivity was 99% for all patients and 100% in the people affected by HIV.
As small clusters continue, the CDC notes that only 1 in 4 eligible people have received both mpox vaccine doses.
Early tecovirimat was associated with shorter time to symptom improvement (by 5.5 days) among participants with severe illness.
Wastewater tests had a sensitivity of 32% for detecting 1 or more people shedding mpox virus, but it was 77% for detecting 15 or more people shedding virus.
Countries reporting the most cases were Spain, Portugal, the UK, and Germany.
The most common adverse event was mild to moderate injection-site pain, which was reported by 60% of vaccinated participants
Mpox disease progression occurred in 5% of those who received Tpoxx early and in 27% of people who received it later or not at all.
Two of the animals died, for a case-fatality rate of 10%, while no animal caretakers were affected.
Cases also continue from China and Singapore in the Western Pacific region.
In US mpox news, some cities are starting to report an increase in cases.