Many of the problems in the mpox response were due to a deflated and exhausted public health workforce across the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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Today's recommendation also sets the stage for transition to the commercial market in the months ahead.
Europe had the biggest mpox rise in September, though the Western Pacific region continues to report the highest levels.
The frequency of resistant isolates remains relatively low compared to the number of patients treated with the drug.
In total, the United States has seen approximately 30,000 mpox cases as of March of 2023.
Cases started declining before the vaccine campaign launched.
Of the 29% of veterans who tested positive for orthopoxvirus, 3% had been vaccinated with Dryvax, and 7% had received ACAM2000.
China is one of the current hot spots in Asia and reported 501 cases in August.
Groups announced new clinical trials and more support for universal flu, MERS, and mpox vaccines.
Of the 399 cases with information on probable transmission routes, 95.2% identified sexual contact, 3.3% cited nonsexual contact, and 0.5% reported healthcare-associated spread.
Researchers say the results suggest that an eye exam should be performed in mpox patients with ocular symptoms and those with moderate to severe skin lesions.