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Half of 399 hospitalized COVID-19 patients developed bacterial infections 48 or more hours after hospitalization, according to a PLOS One study yesterday. The bacterial superinfections were associated most strongly with lung disease, encephalopathy, mechanical ventilation, hospital stay of 8 or more days, and steroid treatment.
A Wellcome report yesterday says more research is needed on drug-resistant bacterial infections (DRIs), but current data indicate that DRIs can be more likely to occur—and have more serious ramifications—in people with health conditions like cancer or who have received extensive treatment such as surgery.
The country is ordering oxygen supplies from other nations, enough for home treatment.
Two doses of the vaccine were safe and 78% effective in preventing infection in pregnant women.
There have been 100 cases of a rare neurologic syndrome in 12.8 million US J&J recipients, mostly in men over 50.
The data, from 2011 through 2018, suggest the agency's antibiotic stewardship efforts are having an impact.
Patients in several high-income countries still have limited access to most of the new antibacterials approved since 2010, and as a result sales revenue for these drugs has been insufficient—findings that highlight the poor commercial prospects for new antibiotics, researchers reported yesterday in Clinical Infectious Diseases.
Today a consensus statement by several leading public health organizations and a commentary in the Annals of Internal Medicine voiced support for mandating COVID-19 vaccinations in US healthcare workers (HCWs).
Two doses of different vaccines were 80% to 89% effective in at-risk patients 65 years and older.
WHO head Tedros urges Moderna and Pfizer to go all out on channeling vaccine supply to COVAX.
The FDA and the CDC said so far there are not enough data to recommend a booster.
People who received the flu vaccine prior to having COVID-19 had less risk of sepsis, stroke, deep vein thrombosis (DVT), and disease requiring emergency or intensive care, according to a study presented at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) this year.
A study of hospital patients in Israel found a link between multidrug-resistant gut bacteria and exposure to commonly used non-antimicrobial drugs (NAMDs), researchers reported last week at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID).
Sixteen African nations report resurgences, and cases have more than doubled in some European countries.
The CDC says vaccines are "one of the most critical strategies to help schools safely resume full operations."
The vaccine had good efficacy against infection and severe disease, but lower than with mRNA vaccines.
"Americans who have been fully vaccinated do not need a booster shot at this time," the agencies say.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The London School of Hygiene and Tropical Medicine (LSHTM) announced today that it is partnering with Johnson & Johnson (J&J) to launch a center focused on research into antimicrobial resistance and tuberculosis (TB).
In Orange County, California, COVID-19 vaccination in healthcare personnel (HCP) was connected with a 94% reduction in HCP cases 3 weeks after second doses of mRNA-based vaccines were administered, according to a JAMA Network Open research letter yesterday.
