Many of the problems in the mpox response were due to a deflated and exhausted public health workforce across the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
Receive the latest infectious disease information.
Of the 85 videos analyzed, only 33% covered all content items that were highlighted in clinical practice guidelines.
Estimated 1-dose protection against symptomatic mpox was 78% after at least 14 days, ranging from 71% to 85% in sensitivity analyses.
The average time for symptom onset between successive cases (serial interval) is 8.5 days, and the time from infection to symptom onset (incubation period) is 5.6 days, new data show.
Severe complications included necrotizing (flesh-eating) skin lesions, lung dysfunction sometimes accompanied by nodules, and secondary infections and sepsis.
Experts conclude that sustained incidence of illness in a few nations, along with underreported detection of cases, was enough to maintain emergency status.
The estimated vaccine effectiveness of one subcutaneous dose of the Jynneos mpox vaccine among men in Israel is 86%.
In a related development, New York City today declared the end of its mpox outbreak, which follows 2 months of low transmission.
The WHO says cases have risen 1%, and, of 11 countries reporting increases, the largest was in Mexico.
Though the findings are promising, researchers are still examining the benefits and drawbacks of the one-dose strategy.
The CDC recorded 466 mpox infections in transgender and gender-diverse adults, which made up 1.7% of adult cases.